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San Francisco 49ers vs Arizona Cardinals: Odds and Predictions

San Francisco 49ers and Arizona Cardinals are NFC West rivals and meet twice every regular season. This page tracks the Kalshi markets for the matchup — moneyline, spread and total — alongside the meetings already played and the ones still to come.Next game: Week 18 · Sun, Jan 10, 2027
49ers

3

vs
Cardinals

2

Last 5 meetings

Next meeting

Sun, Jan 10, 2027

Time TBD · NFL · Week 18

San Francisco 49ers

Arizona Cardinals

Not listed on Kalshi yet. Markets open closer to game day.

Last meeting

Sun, Sep 27, 2026

NFL · Week 3

Arizona Cardinals

30

San Francisco 49ers

36

See this game’s market on Kalshi
Head-to-head

Other 49ers vs Cardinals meetings

The rest of the games these two clubs play against each other — still to come first, then the most recent results — with the Kalshi market for any that is listed.
Sun, Nov 16, 2025 · 4:05 PM ET
San Francisco 49ers
41
Arizona Cardinals
22
NFL · Week 11 · 2025 season
Sun, Sep 21, 2025 · 4:25 PM ET
Arizona Cardinals
15
San Francisco 49ers
16
NFL · Week 3 · 2025 season
Sun, Jan 5, 2025 · 4:25 PM ET
San Francisco 49ers
24
Arizona Cardinals
47
NFL · Week 18 · 2024 season
Sun, Oct 6, 2024 · 4:05 PM ET
Arizona Cardinals
24
San Francisco 49ers
23
NFL · Week 5 · 2024 season
Upcoming

Next games for the 49ers and Cardinals

Every fixture either club plays next, whoever the opponent is, with the Kalshi market where one is listed.
Sun, Nov 15, 2026 · 4:05 PM ET
Los Angeles Rams
Arizona Cardinals
NFL · Week 10
Sun, Nov 15, 2026 · 4:25 PM ET
San Francisco 49ers
Dallas Cowboys
NFL · Week 10
Sun, Nov 22, 2026 · 1:00 PM ET
Arizona Cardinals
Kansas City Chiefs
NFL · Week 11
Sun, Nov 22, 2026 · 8:20 PM ET
Minnesota Vikings
San Francisco 49ers
NFL · Week 11
Sun, Nov 29, 2026 · 4:25 PM ET
Seattle Seahawks
San Francisco 49ers
NFL · Week 12
Sun, Nov 29, 2026 · 4:25 PM ET
Washington Commanders
Arizona Cardinals
NFL · Week 12
Sun, Dec 6, 2026 · 1:00 PM ET
San Francisco 49ers
New York Giants
NFL · Week 13
Sun, Dec 6, 2026 · 4:05 PM ET
Philadelphia Eagles
Arizona Cardinals
NFL · Week 13
Sun, Dec 13, 2026 · 4:25 PM ET
Los Angeles Rams
San Francisco 49ers
NFL · Week 14
Thu, Dec 17, 2026 · 8:15 PM ET
San Francisco 49ers
Los Angeles Chargers
NFL · Week 15
Recent form

Recent games for the 49ers and Cardinals

The last games each club played, whoever the opponent was — with the final score where one is available, and the market page for any that Kalshi listed.
Sun, Nov 8, 2026 · 4:25 PM ET
Arizona Cardinals
Seattle Seahawks
NFL · Week 9
Sun, Nov 8, 2026 · 4:05 PM ET
Las Vegas Raiders
San Francisco 49ers
NFL · Week 9
Sun, Nov 1, 2026 · 1:00 PM ET
Arizona Cardinals
Dallas Cowboys
NFL · Week 8
Sun, Oct 25, 2026 · 4:05 PM ET
Denver Broncos
Arizona Cardinals
NFL · Week 7
Sun, Oct 25, 2026 · 1:00 PM ET
San Francisco 49ers
Atlanta Falcons
NFL · Week 7
Around the league

Other games this week

The rest of that week's league slate, without these two clubs, so the next thing to trade is one click away.
Sun, Nov 15, 2026 · 4:05 PM ET
Seattle Seahawks
Las Vegas Raiders
NFL · Week 10
Thu, Nov 12, 2026 · 8:15 PM ET
Washington Commanders
New York Giants
NFL · Week 10
Sun, Nov 15, 2026 · 1:00 PM ET
Carolina Panthers
New Orleans Saints
NFL · Week 10
Sun, Nov 15, 2026 · 1:00 PM ET
Minnesota Vikings
Green Bay Packers
NFL · Week 10
Sun, Nov 15, 2026 · 9:30 AM ET
New England Patriots
Detroit Lions
NFL · Week 10
Sun, Nov 15, 2026 · 1:00 PM ET
Buffalo Bills
New York Jets
NFL · Week 10
Sun, Nov 15, 2026 · 1:00 PM ET
Houston Texans
Cleveland Browns
NFL · Week 10
Sun, Nov 15, 2026 · 1:00 PM ET
Jacksonville Jaguars
Tennessee Titans
NFL · Week 10
FAQ

49ers vs Cardinals questions

When do the 49ers and Cardinals play next?
The San Francisco 49ers and the Arizona Cardinals meet next in Week 18 in Arizona. They already met in Week 3 in San Francisco this season. Kickoff times come from the NFL’s published schedule and are shown in Eastern time. A game the league flexes keeps its week while its day and time move, so it shows a date without a time until the slot is fixed.
Are the 49ers and Cardinals in the same division?
Yes. The San Francisco 49ers and the Arizona Cardinals both play in the NFC West. Six of every NFL club’s games are inside its own division — the other three opponents, home and away — so 49ers vs Cardinals is one of the six pairings that division is made of.
What is at stake when the 49ers play the Cardinals?
The NFC West, potentially. Head-to-head record is the first tiebreaker the NFL applies between two clubs that finish level in the same division, so if the 49ers and the Cardinals end the season on the same record these two games settle it between them. Division record is the tiebreaker after that, and both of them are division games too.
Can the 49ers and Cardinals meet in the playoffs?
Yes. The 49ers and the Cardinals share a division and therefore a conference, so the bracket can pair them in the wild-card round, the divisional round or the NFC Championship Game — a third meeting on top of the two the regular season already guarantees.
How often do the 49ers and Cardinals play each other?
Every season, twice — once at each club’s stadium. Division opponents are the fixed part of an NFL schedule, so for as long as the 49ers and the Cardinals are both in the NFC West the pairing is on the calendar every year, whatever else the rotation brings.
Where can I follow the 49ers and Cardinals for the rest of the season?
Each club has its own page on Kalshi. The San Francisco 49ers and Arizona Cardinals hubs carry the roster, the weekly injury report, the remaining schedule, the division standings and the market’s read on each club’s division, playoff and Super Bowl chances.
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